medser NuGlow® Copper Peptide Eye Therapy. Copper Peptides Review
Naturally blue in color, this soothing cream is formulated to deliver an extra boost of health essential copper to the skin around the eye. The lightweight therapy combines the power of MD3 Copper Peptide Complex™ with vitamins, botanical antioxidants and an anti-inflammation ingredient. When gently applied onto the skin around the eyes, it smoothes the skin, minimizes the appearance of fine lines, protects the moisture balance and helps reduce puffiness. This moisturizing treatment is formulated for evening use or under makeup and is suitable for extremely dry skin. The light and smooth blend will not weight down delicate skin.
NuGlow® Copper Peptide Eye Therapy With MD3 Copper Benefits.
- smooth fine lines and wrinkles around your eyes
- nourish the delicate skin around the eyes
- help build college & elastin
- reduce dark shadows
- minimize crow’s feet and revitalize
- reflect light for a luminous glow
Key ingredients:
- MD3 Copper™ (MicroDelivery Copper™) – A revolutionary, patent pending copper peptide that uses an advanced and efficient delivery system to delivery skin essential copper to cells. Firms, tones and helps build healthy, vibrant skin while minimizing the appearance of fine lines and wrinkles. Copper also is an antioxidant that helps control vital skin processes
- Glycerin – skin softening humectant
- Dimethicone – helps protect against moisture loss
- Camellia Oleifera (Green tea) Extract – antioxidant, rich in polyphenols
- Camellia Sinesis (White tea) Extract – antioxidant, rich in polyphenols
- Centella Asiatica Extract – also known as gotu kola extract, it boosts circulation, improves the collagen foundation of the skin, and fights oxidation
- Echinacea Purpurea Extract – helps boost the skin’s natural defense systems
- Ceramide 2 – helps protect against moisture loss in the skin
- MD3 Copper™ (MicroDelivery Copper™) – A revolutionary, patent pending copper peptide that uses an advanced and efficient delivery system to delivery skin essential copper to cells. Firms, tones and helps build healthy, vibrant skin while minimizing the appearance of fine lines and wrinkles. Copper also is an antioxidant that helps control vital skin processes
- Glycerin – skin softening humectant
- Dimethicone – helps protect against moisture loss
- Camellia Oleifera (Green tea) Extract – antioxidant, rich in polyphenols
- Camellia Sinesis (White tea) Extract – antioxidant, rich in polyphenols
- Centella Asiatica Extract – also known as gotu kola extract, it boosts circulation, improves the collagen foundation of the skin, and fights oxidation
- Echinacea Purpurea Extract – helps boost the skin’s natural defense systems
- Ceramide 2 – helps protect against moisture loss in the skin
The Magic Ingredient: MD3 Copper Peptides.
NuGlow’s Md3 Copper Peptide is so technologically advanced it is based on numerous domestic and international patents and patents pending.
Put Simply, NuGlow MD3 ™Copper Peptidecomplex aids in the natural process of forming new healthy skin cells which push damaged cells to the surface of the skin where they slough off. NuGlow’s MD3 ™Copper Peptide formulas possess the necessary biochemical actions that can, in a morphological sense, restore skin to a younger appearance without causing skin irritation. Additionally, NuGlow’s formulations tested both hypoallergenic and noncomedogenic.
Here are just some of the positive benenfits studies have shown:
- Clinically proven to improve skin density and help restore skin firmness
- Clinically proven to tighten loose skin and improve skin elasticity
- Clinically proven to reduce the appearance of fine lines and wrinkles
- Powerful collagen and elastin promoter
- Promotes healthier, more youthful looking skin
- Improves smoothness and clarity
- Increases the benefits of natural tissue building processes
- Reduce photodamage and mottled hyperpigmentation
- Evens out tone, improves blotchiness and surface appearance
- Delivers the formula deep within the skin’s surface
- Strongly increase keratinocyte (building block of the epidermis) proliferation in women of 50 year old range
- Pamela Friedman
“They gasped and said: Your skin looks so incredible. I think they all thought I had plastic surgery. But it’s all cause of NuGLOW. If you’re concerned about your looks, try NuGlow.”
Customer reviews and opinions of NuGlow Copper Peptides
From the NuGlow website:
“As the Publisher of Holistic Health Journal I’ve tried a lot of products, but nothing has made me look as young as the NuGLOW products but when I tried NuGLOW I couldn’t believe the difference around my eyes in just 4-5 days. Give NuGlow a shot. I think you’ll see a difference in your skin that you just won’t believe.” Catherine Miller, Publisher, Holistic Health Journal
“I can honestly say that I’ve never used a product line that has done so much, yet cost so little.” – Shelley Mudd
“Nothing has made me look better, or feel better than the NuGlow products.” - Lisa Mazzetti
“I’m a schoolteacher and when I came back to work after summer everyone came up to me and said, ‘How much weight did you lose?’ And I told them I hadn’t lost any. My skin appeared tighter because of NuGLOW. I’m not going to ever stop using it. Buy NuGlow!” - Suzane Perry
“I’ve been a licensed aesthetician for over 20 years and I’ve recommended and tried many different product lines, but the results that I had with NuGlow after only a few weeks were amazing. I would highly recommend it, as a skin care professional, for all skin types.” - Victoria DeLaGuerra
“NuGlow completely evened out my complexion and made my skin very smooth and it’s amazing because I had only been using the products for a week.” - Amy Lee
Independent reviews found on the web:
I love this product. In fact I use all their products. I save money and look great. - By Jane
I tired NuGlow a few months ago and was not sure if it was going to work, but i really wanted to get rid of the stretch marks I got during my first pregnancy. First few weeks I did not notice anything, but after a few week I saw some noticeable changes. – Jessica
NuGlow® Copper Peptide Eye Therapy. Copper Peptides Review is an article review from: Medicinezine.com
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medser
30 November 2011 – Poverty rates in Latin America have dropped to their lowest levels in 20 years, according to a new United Nations report which highlights public spending levels as one of the key factors that has allowed the continent to continue to grow despite the global economic crisis.
Between 1990 and 2010, the poverty rate decreased from 48.4 per cent to 31.4 per cent, while the rate of indigence – or extreme poverty – fell from 22.6 per cent to 12.3 per cent.
The decline in both rates is mainly due to an increase in wages, according to the latest report by the Economic Commission for Latin America and the Caribbean (ECLAC). Public money transfers were also a contributing factor, but to a much lesser extent.
The report, presented yesterday in Santiago, Chile, predicts that the region will close this year with 174 million people living in poverty compared to 177 million in 2010.
“Poverty and inequality continue to decline in the region, which is good news, particularly in the midst of an international economic crisis,” said ECLAC’s Executive Secretary Alicia Bárcena.
The report also forecasts that the poverty rate will continue to drop in the next year. However, it states that the indigence rate may have slightly increased (up to 12.8 per cent) because of the rise in food prices.
The report reveals that public spending, and in particular social expenditure, received a significant boost in most countries over the past 20 years.
“In response to the global economic crisis, the countries opted to temporarily expand public spending rather than to shrink it, which was the action traditionally taken. Although, the emphasis is not always placed on society, expansion still prevented the rise in unemployment and social vulnerability,” the report reads.
The report spotlights countries that had substantial drops in poverty in the past year, including Peru, Ecuador, Argentina, Uruguay and Colombia.
However, Ms. Bárcena warned that progress is threatened by gaps in the productive structure of the region and by labour markets without social protection. Only four out of every 10 workers with formal work are enrolled in the social security system, with a large majority of older persons, women, and workers in rural areas being left out of its benefits.
“To jointly improve productive convergence, labour institutionality and universal social protection in Latin America, steps towards fiscal pacts and social dialogue must be taken,” said Ms. Bárcena.
The report also discusses fertility in the continent, observing that over the past 50 years, the fertility rate dropped rapidly, compared with a moderate drop in adolescent fertility. In addition, a chapter on the Caribbean has been included for the first time, which warns of the high level of unemployment and incidence of HIV/AIDS among young people.
###
According to ECLAC publication presented today:
29 November 2011 – Today, the Economic Commission for Latin America and the Caribbean (ECLAC) reported that between 1990 and 2010 the poverty rate in Latin America dropped by 17 percentage points (from 48,4% to 31,4%) , while the indigence rate fell by 10.3 percentage points (from 22,6% to 12,3%). Therefore, both indicators are at their lowest levels in 20 years.
The publication Social Panorama of Latin America 2011 presented in Santiago, Chile, by the Executive Secretary of ECLAC, Alicia Bárcena, states that the poverty level will drop to 30.4% in 2011, while the indigence rate will increase slightly to 12.8% because the rise in food prices would counteract the predicted rise in household incomes.
This means that the region will close this year with 174 million inhabitants living in poverty, 73 million of which are living in extreme poverty or indigence. In 2010, there were 177 million poor, 70 million of which were living in indigence.
According to ECLAC, the decrease in poverty is primarily due to an increase in labour income. Public monetary transfers also contributed, but to a lesser extent.
“Poverty and inequality continue to decline in the region, which is good news, particularly in the midst of an international economic crisis. However, this progress is threatened by the yawning gaps in the productive structure in the region and by the labour markets which generate employment in low-productivity sectors, without social protection,” warned Alicia Bárcena.
Between 2009 and 2010, significant drops in poverty rates were observed in five countries: Peru, Ecuador, Argentina, Uruguay and Colombia.
Honduras and Mexico were the only countries with significant rises in their poverty rates (1.7% and 1.5% respectively). As for Mexico, the comparison was made with the poverty rate for 2008; therefore, the figure does not only reflect the economic growth in Mexico in 2010, but also the major GDP per capita contractions in 2009.
The publication also highlights that the improvement in distribution was not affected following the economic crisis. Between 2008-2010 in Mexico, Venezuela and Uruguay, the Gini index dropped to an annual rate of over 2% and in El Salvador and Peru it was over 1% per year.
Furthermore, the Social Panorama of Latin America 2011 reveals that public expenditure, and in particular social expenditure, has increased significantly over the past 20 years in the region.
The lowest spending per capita (less than US$ 300) is in Bolivia, Ecuador, Guatemala, Honduras, Nicaragua and Paraguay. These countries spend the most on education. However, in the countries which have social spending per capita of over US$ 1,000, such as Argentina, Brazil, Chile, Costa Rica, Cuba, Trinidad and Tobago and Uruguay, the most spending is on social security and assistance.
In response to the global economic crisis, the countries opted to temporarily expand public spending rather than to shrink it, which was the action traditionally taken. Although, the emphasis is not always placed on society, expansion still prevented the rise in unemployment and social vulnerability.
The ECLAC study also analyses in depth the existing gaps in the world of work and social protection in Latin America.
Not all employees in formal work are enrolled in the social security system: only 4 out of every 10 workers make contributions.
Households with larger numbers of family members, female heads of house and located in rural sectors are those which have less access to contributory protection in the region. Likewise, in 12 out of 17 countries analysed, the social security and pension contributions benefit less than half of older persons.
According to ECLAC, in the medium and long term many countries should reform their social security schemes again to take steps towards rights-based social protection systems, based on contributory and non-contributory finance mechanisms supporting the distribution of resources.
Otherwise, there will continually be problems relating to financing universal social protection in ageing societies with a smaller workforce.
“To jointly improve productive convergence, labour institutionality and universal social protection in Latin America, steps towards fiscal pacts and social dialogue must be taken,” stated Ms. Bárcena.
The ECLAC publication also discusses the situation of fertility in Latin America. Over the past 50 years, the global fertility rate observed dropped rapidly, compared with the moderate drop in adolescent fertility. In addition, a chapter on the Caribbean has been included for the first time, which warns of the high level of unemployment and the incidence of HIV/AIDS among young people in the subregion.
###
SUMMARY
For Social Panorama of Latin America, the main challenge is to foster a more in-depth examination of social gaps and the mechanisms that reproduce or decrease them. The previous edition of Social Panorama homed in on inequality gaps and their intergenerational reproduction and paid particular attention to the formative years of individuals, their transition to adult life and the role of social expenditure and transfers in meeting the needs of new generations during their early years. It showed how the life cycle path is determined by differences in skill development and how inequality and poverty become entrenched as people move from one stage of life to the next.
The 2011 edition of Social Panorama of Latin America takes a more in-depth look at the chain that produces and reproduces social gaps; it addresses other spheres as well. It focuses on how structural heterogeneity (productivity gaps in the national economies), labour segmentation and gaps in social protection are linked along the chain. Demographic factors such as fertility differentiated by education and income level are discussed, as are more specific patterns of risk and exclusion like those impacting young people in the Caribbean.These gaps make for an ambivalent scenario in the region, combining structural tendencies that reinforce them with recent, favourable developments that open new possibilities for advancing towards less unequal societies with broader access to well-being. Poverty and inequality are decreasing in the region; the main reasons are, first, rising labour income and, second, increasing public transfers to the most vulnerable sectors. But the productive gaps are still rigid, and there is still little mobility for specific groups in low-productivity sectors (especially women in lower-income socioeconomic groups) whose income has not increased. Fertility is declining substantially and can mean greater possibilities for well-being among families with fewer dependents.
###
LATIN AMERICA: POVERTY AND INDIGENCE, 1980-2011a
(Percentages and millions of persons)
Source: Economic Commission for Latin America and the Caribbean (ECLAC), on the basis of special tabulations of
data from household surveys conducted in the respective countries.
a /Estimate for 18 countries of the region plus Haiti. The figures above the bars represent the percentage and total
number of poor persons (indigent plus non-indigent poor), respectively. The figures for 2011 are projections.
###
LATIN AMERICA (18 COUNTRIES): PERSONS LIVING IN POVERTY AND INDIGENCE,
AROUND 2002, 2009 AND 2010
(Percentages)
Source: Economic Commission for Latin America and the Caribbean (ECLAC), on the basis of special tabulations of data from household surveys conducted in the relevant countries.
a. Urban areas.
b. Figures from the Misión para el empalme de las series de empleo, pobreza y desigualdad (MESEP). These figures do not include the changes in the measurement of poverty made in 2011 by the National Planning Department (DNP) of Colombia.
c. Figures from the National Institute of Statistics and Information (INEI) of Peru.
###
> About Economic Commission for Latin America (ECLAC)
The Economic Commission for Latin America (ECLA) – the Spanish acronym is CEPAL- was established by Economic and Social Council resolution 106(VI) of 25 February 1948 and began to function that same year. The scope of the Commission’s work was later broadened to include the countries of the Caribbean, and by resolution 1984/67 of 27 July 1984, the Economic Council decided to change its name to the Economic Commission for Latin America and the Caribbean (ECLAC); the Spanish acronym, CEPAL, remains unchanged.
ECLAC, which is headquartered in Santiago, Chile, is one of the five regional commissions of the United Nations. It was founded with the purpose of contributing to the economic development of Latin America, coordinating actions directed towards this end, and reinforcing economic ties among countries and with other nations of the world. The promotion of the region’s social development was later included among its primary objectives.
In June 1951, the Commission established the ECLAC subregional headquarters in Mexico City, which serves the needs of the Central American subregion, and in December 1966, the ECLAC subregional headquarters for the Caribbean was founded in Port-of-Spain, Trinidad and Tobago. In addition, ECLAC maintains country offices in Buenos Aires, Brasilia, Montevideo and Bogotá, as well as a liaison office in Washington, D.C.
###
> United Nations (UN).
The United Nations was established on 24 October 1945 by 51 countries committed to preserving peace through international cooperation and collective security. Today, nearly every nation in the world belongs to the UN: membership totals 192 countries.
When States become Members of the United Nations, they agree to accept the obligations of the UN Charter, an international treaty that sets out basic principles of international relations. According to the Charter, the UN has four purposes:
- to maintain international peace and security;
- to develop friendly relations among nations;
- to cooperate in solving international problems and in promoting respect for human rights;
- and to be a centre for harmonizing the actions of nations.
###
* The above story is adapted from materials provided by United Nations (UN)
** More information at United Nations (UN)
Latin American poverty levels fall to lowest in two decades, UN report finds is an article review from: Medicinezine.com
- MedicinEzine.com is a carefully selected collection of articles about alternative or complementary forms of medicine products. MedicinEzine.com provides free registration, customer reviews and information, allows customer comments, user comments. MedicinEzine.com
- MedicinEzine.com is a World Journal of medicine articles and reviews, product reviews, customer reviews and opinions. MedicinEzine.com provides the latest medical news and headlines from the world of medicine and healthcare today and tomorrow. MedicinEzine.com News
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medser Syrian crisis reaching stage of civil war, UN human rights chief says
Syrian women protesting in May 2011
1 December 2011 – The deteriorating situation in Syria is now close to a civil war and the death toll from the nine-month crackdown by the country’s security forces against protesters has passed at least 4,000, the United Nations human rights chief said today.
Navi Pillay, the UN High Commissioner for Human Rights, told journalists in Geneva that 4,000 was a conservative estimate, with “the reliable information coming to us… that it’s much more than that.”
Ms. Pillay will address a special session tomorrow of the UN Human Rights Council, which is meeting in Geneva to discuss this week’s release of an independent international commission of inquiry into the crackdown.
That three-member commission, established by the Council, found evidence that Syria’s military and security forces have committed crimes against humanity since March, when a public uprising began across Syria, in line with similar movements across North Africa and the Middle East.
The commission’s report is based on interviews with more than 200 victims and witnesses of human rights violations, including civilians and defectors from the military and security forces.
Aside from its findings, the commission called on the Syrian Government to immediately end the ongoing rights violations, to initiate investigations of these incidents and to bring the perpetrators to justice.
Speaking today, Ms. Pillay warned that as more defectors threatened to take up arms, there is an increasing threat of “a civil war and at the moment that is how I am characterizing this.”
### > United Nations (UN).
The United Nations was established on 24 October 1945 by 51 countries committed to preserving peace through international cooperation and collective security. Today, nearly every nation in the world belongs to the UN: membership totals 192 countries.
When States become Members of the United Nations, they agree to accept the obligations of the UN Charter, an international treaty that sets out basic principles of international relations. According to the Charter, the UN has four purposes:
- to maintain international peace and security;
- to develop friendly relations among nations;
- to cooperate in solving international problems and in promoting respect for human rights;
- and to be a centre for harmonizing the actions of nations.
### * The above story is adapted from materials provided by United Nations (UN) ** More information at United Nations (UN)
Syrian crisis reaching stage of civil war, UN human rights chief says is an article review from: Medicinezine.com
- MedicinEzine.com is a carefully selected collection of articles about alternative or complementary forms of medicine products. MedicinEzine.com provides free registration, customer reviews and information, allows customer comments, user comments. MedicinEzine.com
- MedicinEzine.com is a World Journal of medicine articles and reviews, product reviews, customer reviews and opinions. MedicinEzine.com provides the latest medical news and headlines from the world of medicine and healthcare today and tomorrow. MedicinEzine.com News
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medser Bollywood star to focus on child nutrition in new role as UNICEF ambassador
30 November 2011 – One of Bollywood’s biggest names, the actor-producer Aamir Khan, today became the newest Goodwill Ambassador for the United Nations Children’s Fund (UNICEF), teaming up with the UN agency to promote better nutrition for children.
Mr. Khan, 46, will use his profile to spotlight nutrition issues in India, where as many as one out of every two children is classified as malnourished, leaving them vulnerable to disease and health problems.
“I realize there is a lot to be done and I hope that by lending my voice I can make a difference to the lives of children and hereby to the future of our country,” Mr. Khan said after the appointment was announced in New Delhi, the capital.
The ambassador – who has already been working with UNICEF, the Government and prominent figures to create a national campaign on malnutrition – said he will focus his advocacy work on India’s most vulnerable and marginalized children.
Karin Hulshof, UNICEF’s representative in India, described Mr. Khan as a “compelling advocate” who can help to transform the lives of countless children.
“His voice and unwavering commitment will help to reach every child, irrespective of their background, caste or religion. India is a rising power on the world stage. And yet, so many rights and entitlements of children remain to be fulfilled.”
###
Actor and producer Aamir Khan appointed UNICEF Ambassador
NEW DELHI, India
30 November 2011 — UNICEF is delighted to announce the appointment of the Padma Bhushan award-winning actor and producer Aamir Khan, as its Ambassador promoting nutrition for children.
In his new role, Aamir Khan will participate actively to create a better life for millions of children in India. As a representative of UNICEF, Aamir Khan will build on his personal interest in children’s issues to support UNICEF’s mission to ensure that every child in this country survives and thrives.
“I am honored to formalize my association with UNICEF as their Ambassador to help raise awareness on the issue of malnutrition amongst children.” said Aamir Khan at today’s signing ceremony in Delhi. “Over the past one year, I have worked with the team at UNICEF, partners from the Government, Citizen’s alliance and Prasoon Joshi’s and his team, to create a nationwide campaign against Malnutrition.”
In India, one out every two children is malnourished, leaving them vulnerable to poor health and disease, particularly children from the country’s most remote and disadvantaged communities.
“I realize there is a lot to be done and I hope that by lending my voice I can make a difference to the lives of children and hereby to the future of our country. Partnering with UNICEF will enable me to advocate for the rights of the most vulnerable and marginalized children in India.” He added.
Secretary, Ministry of Women and Child Development Mr. D. K Sikri and UNICEF Representative in India, Karin Hulshof both welcomed the appointment.
“We know Aamir Khan as a leading star of Indian cinema. He is also a compelling advocate, with an enormous drive and commitment, to transform and improve the situation of children in the country. ” Ms. Hulshof said.
“I cannot stress enough how fortunate we are to welcome him into the UNICEF family in India. His voice and unwavering commitment will help to reach every child, irrespective of their background, caste or religion. India is a rising power on the world stage. And yet, so many rights and entitlements of children remain to be fulfilled. Working side by side, we will address this and combine our collective efforts to create a world fit for children.” She added.
UNICEF Ambassadors are celebrities with a demonstrated commitment to improving the lives of children. Highly talented in their individual right, they all share an ability to bring children’s issues to attention, to galvanize support from the public and lead decision makers and to raise
urgently needed funds for vital UNICEF programmes.
About UNICEF
UNICEF works in 190 countries and territories to help children survive and thrive, from early childhood through adolescence. The world’s largest provider of vaccines for developing countries, UNICEF supports child health and nutrition, good water and sanitation, quality basic education for all boys and girls, and the protection of children from violence, exploitation, and AIDS. UNICEF is funded entirely by the voluntary contributions of individuals, businesses, foundations and governments. For more information about UNICEF and its work visit: www.unicef.org
###
> United Nations (UN).
The United Nations was established on 24 October 1945 by 51 countries committed to preserving peace through international cooperation and collective security. Today, nearly every nation in the world belongs to the UN: membership totals 192 countries.
When States become Members of the United Nations, they agree to accept the obligations of the UN Charter, an international treaty that sets out basic principles of international relations. According to the Charter, the UN has four purposes:
- to maintain international peace and security;
- to develop friendly relations among nations;
- to cooperate in solving international problems and in promoting respect for human rights;
- and to be a centre for harmonizing the actions of nations.
###
* The above story is adapted from materials provided by United Nations (UN)
** More information at United Nations (UN)
Bollywood star to focus on child nutrition in new role as UNICEF ambassador is an article review from: Medicinezine.com
- MedicinEzine.com is a carefully selected collection of articles about alternative or complementary forms of medicine products. MedicinEzine.com provides free registration, customer reviews and information, allows customer comments, user comments.MedicinEzine.com
- MedicinEzine.com is a World Journal of medicine articles and reviews, product reviews, customer reviews and opinions. MedicinEzine.com provides the latest medical news and headlines from the world of medicine and healthcare today and tomorrow.MedicinEzine.com News
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- At UNICEF centre, British and Danish royals highlight plight of children in Horn of Africa
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- Seminar to Focus on Link Between Nutrition and Fertility …
- Zidane and Ronaldo target hunger in annual all-star UN charity soccer match
medser Aging stem cells may explain higher prevalence of leukemia, infections among elderly, study shows
November 28, 2011 Human stem cells aren’t immune to the aging process, according to scientists at the Stanford University School of Medicine. The researchers studied hematopoietic stem cells, which create the cells that comprise the blood and immune system. Understanding when and how these stem cells begin to falter as the years pass may explain why some diseases, such as acute myeloid leukemia, increase in prevalence with age, and also why elderly people tend to be more vulnerable to infections such as colds and the flu.
“We know that immune system function seems to decline with increasing age,” said Wendy Pang, MD. “This is the first study comparing the function and gene expression profiles of young and old purified, human hematopoietic stem cells, and it tells us that these clinical changes can be traced back to stem cell function.”
Specifically, the researchers found that hematopoietic stem cells from healthy people over age 65 make fewer lymphocytes — cells responsible for mounting an immune response to viruses and bacteria — than stem cells from healthy people between ages 20 and 35. (The cells were isolated from bone marrow samples.) Instead, elderly hematopoietic stem cells, or HSCs, have a tendency to be biased in their production of another type of white blood cell called a myeloid cell. This bias may explain why older people are more likely than younger people to develop myeloid malignancies.
The study was published online Nov. 28 in the Proceedings of the National Academy of Sciences. Pang, who is in the Medical Science Training Program at Stanford, is the first author of the research; professor of pathology Irving Weissman, MD, is the senior author. Weissman is also the director of Stanford’s Institute for Stem Cell Biology and Regenerative Medicine.
Pang began the study to understand whether human HSCs aged like mouse HSCs. Previous studies had shown that mouse HSCs change in number and function as a laboratory mouse grows older. She obtained HSCs from 15 healthy elderly people and 28 healthy young people and compared their prevalence, distribution and cell cycle profile.
She found that HSCs comprised a greater proportion of bone marrow cells in older people than in younger people. They were also more likely to be actively dividing than younger HSCs. But their greater numbers and increased proliferation didn’t translate into greater efficiency; like a top wobbling out of control as its rotation slows, the aging HSCs instead appear to be unsuccessfully trying to keep up with the demands of everyday life.
When Pang purified the HSCs and grew them in laboratory dishes, she found that HSCs from older people were less able to differentiate into B lymphocytes and more likely to become myeloid cells. Furthermore, immune-deficient laboratory mice given transplants of older, human HSCs exhibited a higher proportion of myeloid to lymphoid cells in their bone marrow in the weeks to months after the transplant.
Finally, Pang examined the gene expression profile of the two sets of human HSCs, as well as five samples of HSCs from people ages 42 to 61. She found that HSCs from elderly donors express comparatively higher levels of several age-related genes associated with the cell cycle, proliferation and development, as well as genes associated with DNA repair and cell death. The higher levels of these genes suggests the cells are less likely to wait quietly on the sidelines until new blood or immune cells are needed and are instead entering the cell cycle inappropriately.
Overall, the results mirror those seen in studies of HSCs from laboratory mice of varying ages. They suggest that human HSCs struggle as a person ages, and that this struggle can sometimes lead not only to inadequate immune responses, but also to inappropriate growth and specific types of blood cancers, such as acute myeloid leukemia. They also contribute valuable information for the study of many other conditions.
“In both mice and humans, the puzzle has been how the system ages,” said Weissman, who is also the Virginia & D.K. Ludwig Professor for Clinical Investigation in Cancer Research and a member of Stanford’s Cancer Institute. “Because HSCs in old mice and humans are derived from the HSCs they had in their youth, there are two possibilities to describe how these differences occur. Either individual, young HSCs change their gene expression patterns as they age, undergoing heritable adaptations that favor the myeloid lineage, or each young HSC already has a specific lineage bias and is battling for precious niches through the natural selection of aging, which favors those biased toward myeloid cells.” Understanding which possibility is true could help clinicians of the future encourage the survival of HSCs with more-appropriate properties in patients with age-related diseases, Weissman believes.
“These findings will also serve as an important baseline for future studies of age-related diseases, such as myeloid dysplastic syndrome, anemia and leukemia,” said Pang. “Now that we know how HSCs change and function in elderly individuals who are not ill, we should be able to tease out disease-associated changes from normal age-associated phenomena.”
In addition to Pang and Weissman, other Stanford researchers involved in the study include assistant professor of medicine Elizabeth Price, MD; instructor of pathology Debashis Sahoo, PhD; professor of orthopedic surgery William Maloney, MD; and professor of medicine Stanley Schrier, MD.
The research was supported by the Stanford Medical Scientist Training Program, the Siebel Stem Cell Institute, the Thomas and Stacey Siebel Foundation and the National Institutes of Health. Information about Stanford’s Department of Pathology, in which the research was conducted, is available at http://pathology.stanford.edu.
Irving Weissman, MD.
Professor, Pathology – Stem Cell Institute
Member, Bio-X
Member, Cancer Center
Professor, Developmental Biology
Professor (By courtesy), Biology (School of Humanities and Sciences)
> Administrative Appointments
Director, Institute of Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine (2003 – present)
> Honors and Awards
Passano Award, The Passano Foundation (2009)
Rosentiel Award, Brandeis University (2009)
Fellow, American Association for the Advancement of Science (2008)
Robert Koch Award, Koch Foundation (2008)
Honoree of the Arthritis Foundation of Northern California Chapter’s 2007 Tribute Dinner, Arthritis Foundation (2007)
I & H Wachter Award, I & H Wachter Foundation (2007)
Honorary Doctorate, Mount Sinai School of Medicine (2007)
John Scott Award, City of Philadelphia (2006)
American-Italian Cancer Foundation Prize for Scientific Excellence in Medicine, American-Italian Cancer Foundation (2006)
Honorary Doctorate, Columbia University (2006)
The Commonwealth Club of California 18th Annual Distinguished Citizen Award, Commonwealth Club of California (2006)
Jeffrey Modell “Dare to Dream” Award, Jeffrey Modell Foundation (2005)
The Linus Pauling Medal for Outstanding Contributions to Science, Stanford University (2005)
Rabbi Shai Shacknai Memorial Prize in Immunology and Cancer Research, The Lautenberg Center for General and Tumor Immunology (2004)
Medal for Distinguished Contributions to Biomedical Research, New York Academy of Medicine (2004)
Alan Cranston Awardee, Alliance for Aging Research (2004)
Jessie Stevenson Kovalenko Medal, National Academy of Sciences Council (2004)
Bass Award, Society of Neurological Surgeons (2003)
Award for Outstanding Contribution to Cancer Biology, Pasarow Foundation (1989)
Election to the Institute of Medicine, National Academy of Sciences (1989)
> Professional Education
MD: Stanford University, Medicine (1965)
BS: Montana State College, Pre-med (1961)
> Graduate & Fellowship Program Affiliations
Cancer Biology
Developmental Biology
Immunology
> Current Research Interests
Irving L. Weissman’s research encompasses the phylogeny and developmental biology of the cells that make up the blood-forming and immune systems. His laboratory identified and isolated the blood-forming stem cell from mice, and has defined, by lineage analysis, the stages of development between the stem cells and mature progeny (granulocytes, macrophages, etc.). This required developing and cloning stromal cells of the hematolymphoid microenvironmentsfrom the bone marrow for myeloid and B cells, and from the thymus for T cells. While the adhesion molecules and factors from these stromal cells proved important as molecules (and the genes that encode them) for myeloid and B cells, the analysis of T cell development required in vivo studies of thymic development. In addition, the Weissman laboratory has pioneered the study of the genes and proteins involved in cell adhesion events required for lymphocyte homing to lymphoid organs in vivo, either as a normal function or as events involved in malignant leukemic metastases.
The Weissman laboratory also has a small group at Hopkins Marine Station, where they have developed a model organism for laboratory and field study of allorecognitionthe invertebrate counterpart of transplantation immunity. Working with the protochordate Botryllus schlosseri (which has a chordate larval stage and an invertebrate adult form) they have identified a single major gene locus that governs rapid allorecognition, and 2-3 other loci involved in delayed allorecognition events. They are using this model to study the genes, proteins, and cells that govern protochordate allorecognition, and the effects of these genes on their population dynamics in the field.
###
* Stanford University Medical Center integrates research, medical education and patient care at its three institutions – Stanford University School of Medicine, Stanford Hospital & Clinics and Lucile Packard Children’s Hospital.
** The above story is adapted from materials provided by Stanford University School of Medicine
________________________________________________________________
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medser Aging stem cells have clinical implications, say Stanford scientists
At the risk of being overly depressing, we’re all getting older. And there’s more to bemoan than just the gray hairs and wrinkles that might be popping up. Every cell in our body is aging, including the hematopoietic stem cells that generate our blood cells and immune system. According to our release:
Specifically, the researchers found that hematopoietic stem cells from healthy people over age 65 make fewer lymphocytes — cells responsible for mounting an immune response to viruses and bacteria — than stem cells from healthy people between ages 20 and 35. (The cells were isolated from bone marrow samples.) Instead, elderly hematopoietic stem cells, or HSCs, have a tendency to be biased in their production of another type of white blood cell called a myeloid cell. This bias may explain why older people are more likely than younger people to develop myeloid malignancies.
It could also be why elderly people find it hard to shake off colds, flu and other viruses, say graduate student Wendy Pang, MD and stem cell biologist Irving Weissman, MD, who co-authored the study in today’s Proceedings of the National Academy of Sciences.
“In both mice and humans, the puzzle has been how the system ages,” said Weissman, who is also the Virginia & D.K. Ludwig Professor for Clinical Investigation in Cancer Research and a member of Stanford’s Cancer Institute. “Because HSCs in old mice and humans are derived from the HSCs they had in their youth, there are two possibilities to describe how these differences occur. Either individual, young HSCs change their gene expression patterns as they age, undergoing heritable adaptations that favor the myeloid lineage, or each young HSC already has a specific lineage bias and is battling for precious niches through the natural selection of aging, which favors those biased toward myeloid cells.” Understanding which possibility is true could help clinicians of the future encourage the survival of HSCs with more-appropriate properties in patients with age-related diseases, Weissman believes.
By Krista Conger
Stanford School of Medicine
Irving Weissman, MD.
Professor, Pathology – Stem Cell Institute
Member, Bio-X
Member, Cancer Center
Professor, Developmental Biology
Professor (By courtesy), Biology (School of Humanities and Sciences)
> Administrative Appointments
Director, Institute of Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine (2003 – present)
> Honors and Awards
Passano Award, The Passano Foundation (2009)
Rosentiel Award, Brandeis University (2009)
Fellow, American Association for the Advancement of Science (2008)
Robert Koch Award, Koch Foundation (2008)
Honoree of the Arthritis Foundation of Northern California Chapter’s 2007 Tribute Dinner, Arthritis Foundation (2007)
I & H Wachter Award, I & H Wachter Foundation (2007)
Honorary Doctorate, Mount Sinai School of Medicine (2007)
John Scott Award, City of Philadelphia (2006)
American-Italian Cancer Foundation Prize for Scientific Excellence in Medicine, American-Italian Cancer Foundation (2006)
Honorary Doctorate, Columbia University (2006)
The Commonwealth Club of California 18th Annual Distinguished Citizen Award, Commonwealth Club of California (2006)
Jeffrey Modell “Dare to Dream” Award, Jeffrey Modell Foundation (2005)
The Linus Pauling Medal for Outstanding Contributions to Science, Stanford University (2005)
Rabbi Shai Shacknai Memorial Prize in Immunology and Cancer Research, The Lautenberg Center for General and Tumor Immunology (2004)
Medal for Distinguished Contributions to Biomedical Research, New York Academy of Medicine (2004)
Alan Cranston Awardee, Alliance for Aging Research (2004)
Jessie Stevenson Kovalenko Medal, National Academy of Sciences Council (2004)
Bass Award, Society of Neurological Surgeons (2003)
Award for Outstanding Contribution to Cancer Biology, Pasarow Foundation (1989)
Election to the Institute of Medicine, National Academy of Sciences (1989)
> Professional Education
MD: Stanford University, Medicine (1965)
BS: Montana State College, Pre-med (1961)
> Graduate & Fellowship Program Affiliations
Cancer Biology
Developmental Biology
Immunology
###
* Stanford University Medical Center integrates research, medical education and patient care at its three institutions – Stanford University School of Medicine, Stanford Hospital & Clinics and Lucile Packard Children’s Hospital.
** The above story is adapted from materials provided by Stanford University School of Medicine
________________________________________________________________
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- Food, glorious food: Stanford’s first food summit
medser Scientists identify defect in brain cell channel that may cause autism-like syndrome
Neuroscientists at Stanford University School of Medicine have homed in on potential differences in autistic people’s brain cells by studying brainlike spheres grown in an elaborate process from skin cells.
Ricardo Dolmetsch, PhD, associate professor of neurobiology
The scientists studied cells from patients with Timothy syndrome, a rare genetic condition that is associated with one of the most penetrant forms of autism: In other words, most people with the Timothy syndrome mutation have autism as a symptom, among other problems.
Autism is a spectrum of developmental disorders of impaired social and verbal interaction. Currently, no medication exists to treat its underlying causes, according to the U.S. National Library of Medicine. Understanding what goes awry in autistic brain development could improve prospects for treating the condition.
In this study, the scientists suggest that the autism in Timothy syndrome patients is caused by a gene mutation that makes calcium channels in neuron membranes defective, interfering with how those neurons communicate and develop. The flow of calcium into neurons enables them to fire, and the way that the calcium flow is regulated is a pivotal factor in how our brains function.
The researchers also found brain cells grown from individuals with Timothy syndrome resulted in fewer of the kind of cells that connect both halves of the brain, as well as an overproduction of two of the brain’s chemical messengers, dopamine and norepinephrine. Furthermore, they found they could reverse these effects by chemically blocking the faulty channels.
Postdoctoral scholar Sergiu Pasca, MD, and Ricardo Dolmetsch, PhD, associate professor of neurobiology, led the study, published online Nov. 27 in Nature Medicine. Dolmetsch, a biophysicist, redirected his research to study autism after his son was diagnosed with autism. It’s unclear what leads to autism, but its incidence is increasing, he said.
The gaps in our understanding of the causes of psychiatric disorders such as autism have made them difficult to treat. Perhaps the biggest obstacle to research into autism and other psychiatric and neurological diseases is that scientists can’t get living brain cell samples from people with these conditions, for obvious reasons. Dolmetsch and his colleagues figured out a solution to this dilemma, using a novel approach involving what are known as induced pluripotent stem cells, or iPS cells.
“We developed a way of taking skin cells from humans with Timothy syndrome and converting them into stem cells, then converting those stem cells into neurons,” said Dolmetsch.
The scientists grew these iPS cells as free-floating clumps in a nutrient-rich solution, later transferring the clumps to tissue culture plates. Here, some of them formed three-dimensional, brainlike spheres whose cells later migrated outward and matured into neurons. These neurons formed three distinct layers, a good first approximation of living tissue in the brain. By visualizing these neurons under a microscope and quantifying their gene expression, the scientists were able to characterize at the cellular level abnormalities that may be associated with autism.
The neurons grown from Timothy-syndrome iPS cells showed larger-than-normal spikes in calcium levels, suggesting the calcium channels lost their ability to shut off. This set off dramatic changes in neuronal signaling, reconfiguring how genes were expressed.
The cerebral cortex, the outer layer of the brain, has six distinct layers. In Timothy syndrome cell cultures, the proportion of neurons of specific layers differed from that in normal brains — additional biological evidence for the disorder. The neurons grown from the Timothy syndrome cells were less characteristic of lower-level neurons, which include neurons that bridge the left and right halves of the brain via the bundle of fibers known as the corpus callosum. This reinforces the view that autism results from defects in brain connectivity.
Pasca and Dolmetsch had an “aha” moment when they realized the neurons grown from Timothy syndrome cells were making too much of the enzyme most critical for producing dopamine and norepinephrine, which play an important role in sensory processing and social behavior. The realization may offer important clues about what causes the problems seen in autism.
To determine whether the enzyme upsurge was reversible, the scientists treated the neurons with a chemical that blocks the defective calcium channels, called roscovitine. They saw a nearly 70 percent reduction in the proportion of cells producing the enzyme, confirming the defective calcium channel was the culprit in producing too much dopamine and norepinephrine. Such reversibility suggests that certain cellular abnormalities in autism may be treatable.
Dolmetsch warned, however, that roscovitine is not currently approved for use in humans and has never been tested in children. While it is currently in clinical trials for lung cancer, it reportedly causes nausea and other side effects. “The reported side effects are probably due to the fact that, in addition to targeting the channel that is mutated in autism, roscovitine also inhibits kinases that are required for cell proliferation,” he said. “We think that roscovitine is a good starting point, but probably has to be optimized before it would be useful for autism.”
In the meantime, the study represents a major achievement with its success in developing a technique to recreate how the neurons of individuals with Timothy syndrome develop in a lab setting. It’s the first time it’s been possible to study the disorder in human cells rather than mouse cells, so it represents a better clinical model, Dolmetsch said.
“These results could lead to a very powerful research tool,” he said. “It’s human psychiatric disease in a petri dish.”
Researchers from UCLA contributed to the study. Other authors from Stanford were postdoctoral scholars Thomas Portmann, PhD, Masayuki Yazawa, PhD, and Oleksandr Shcheglovitov, PhD; clinical researcher Anca Pasca, MD; neurology researcher Branden Cord MD, PhD; associate professor of neurosurgery Theo Palmer, PhD; Sachiko Chikahisa, PhD, and research professor of psychiatry and behavioral sciences Nishino Seiji, MD, PhD, both of the Sleep and Circadian Neurobiology Laboratory; clinical assistant professor of medical genetics Jonathan Bernstein, MD, PhD; and associate professor of psychiatry and behavioral sciences Joachim Hallmayer, MD.
Financial support was provided by the National Institutes of Health, a Simons Foundation grant, International Brain Research Organization, the Tashia and John Morgridge Endowed Fellowship, Japan Society of the Promotion for Science, American Heart Association Western States, the Swiss National Science Foundation, the California Institute for Regenerative Medicine and several individual donors. Information about the Department of Neurobiology, in which the study was conducted, is available at http://neurobiology.stanford.edu/.
###
Ricardo Dolmetsch, PhD. Bio.
Ricardo Dolmetsch, PhD, associate professor of neurobiology.
- Associate Professor, Neurobiology
- Member, Bio-X
> Honors and Awards
- Society for Neuroscience Young Investigator Award, Society for Neuroscience (2007)
- NIH Pioneer Award, National Institutes of Health (2008-2013)
- Searle Scholar, Searle Foundation (2004-2006)
- Career Award in the Biomedical Sciences, Burroughes Welcome Fund (2002-2007)
- McKnight Scholar, McKnight Endowment for Neurosciences (2004-2006)
- Helen Hay Whitney Fellow, Helen Hay Whitney Foundation (1999-2002)
> Professional Education
Postdoctoral Fellow: Harvard Medical School, Neuroscience (2003)
Ph.D.: Stanford University, Neuroscience (1997)
B.Sc.: Brown University, Neuroscience (1990
> Graduate & Fellowship Program Affiliations
Chemical and Systems Biology
Neurosciences
> Current Research Interests
Our lab studies the underlying neurobiology of autism and other neuro-developmental disorders. We are particularly interested in understanding how electrical activity and calcium signals control the development of the brain and how this is altered in children with autism spectrum disorders. We are also developing new tools to study and repair the developing brain.
###
* Stanford University Medical Center integrates research, medical education and patient care at its three institutions – Stanford University School of Medicine, Stanford Hospital & Clinics and Lucile Packard Children’s Hospital.
** The above story is adapted from materials provided by Stanford University School of Medicine
________________________________________________________________
- MedicinEzine.com is a carefully selected collection of articles about alternative or complementary forms of medicine products. MedicinEzine.com provides free registration, customer reviews and information, allows customer comments, user comments. MedicinEzine.com
- MedicinEzine.com is a World Journal of medicine articles and reviews, product reviews, customer reviews and opinions. MedicinEzine.com provides the latest medical news and headlines from the world of medicine and healthcare today and tomorrow. MedicinEzine.com News
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medser Sections for Tom Venuto – Burn That Fat Review
- Tom Venuto: Get Rid of that Stubborn Tummy Fat
- Tom Venuto’s Championship-Winning Ab Workout Routine
- Tom Venuto: 6 Nutrition Secrets For Great Abs
Tom Venuto is a lifetime natural bodybuilder, certified strength and conditioning specialist (CSCS) and a certified personal trainer (CPT). Tom is the author of “Burn the Fat, Feed The Muscle,” which teaches you how to get lean without drugs or supplements using methods of the world’s best bodybuilders and fitness models. Learn how to get rid of stubborn abdominal fat and increase your metabolism by visiting: www.BurnTheFat.com
6 Nutrition Secrets For Great Abs
In the previous two installments of this series I discussed the science and training about revealing abdominal muscles.
That leads us to nutrition. Many people say that “abdominals are made in the kitchen, not in the gym,” and there’s a lot of truth to that. You can do thousands of reps of ab work every week, but if your nutrition is not in order, you can forget about getting a great set of 6-pack abs.
Eat about 15-20% below your calorie maintenance level. If you use a more aggressive calorie deficit of 25-30%, then do not keep calories too low for too long; increase calories to maintenance or maintenance +10-15% 1-2 days per week.
Spread your calories into 5-6 smaller meals instead of 2-3 big ones. Be very conscious of portion size. If you eat too much of anything (even “healthy” food), you can say goodbye to your abs. Period.
Eat a source of complete, high quality lean protein with each meal (egg whites, lean meat, fish, protein powder, etc.)
Choose natural, complex carbs such as vegetables, oatmeal, yams, potatoes, beans, brown rice and whole grains. Start with aprox. 50% of your calories from natural carbs and reduce carbs slightly (esp. late in the day) if you are not losing fat. Avoid refined, simple carbs that contain white flour or white sugar
Keep total fats low and saturated fats low. Aim for 20% of your total calories from fat (and no more than 30%). A little bit of “good fat” like flax oil, fish fat, nuts & seeds, etc. is better than a no fat diet. Essential fatty acids actually assist the fat burning process.
Drink plenty of water – a gallon is a good ballpark to shoot for if you are physically active.
1000+ reps of daily ab work is an amazing feat of endurance, but that’s not how you get visible, 6-pack abs! If you were to do 1,000 reps of ab exercises every day, you would have outstanding development in your abdominal muscles and you would definitely have great muscular endurance. Unfortunately, if your abs are covered up with a layer of fat, you will never see them even if you do 10,000 reps a day!
You Condition and Strengthen Your Abs With Specific Ab Exercises…
But The Secret To Seeing Your Abs Is Reducing Your Body Fat!
I once saw a photo of a man who broke one of the Guiness World Records for sit ups. It was the most paradoxical thing, because this man did not have any abdominal muscle definition. He was not obese or overweight at all, mind you, but he had a small enough layer of body fat that the muscular defintion did not show through. I’ve never seen a better real life example which demonstrates the basic principle discussed in this article.
You get great abs from reducing your body fat, and you reduce your body fat by creating a caloric deficit through nutrition and metabolism-stimulating and calorie-burning exercise.
I’ve spent my entire career – through more than 18 years and 28 bodybuilding competitions – studying the science and practicing the art of body fat reduction. I speak from experience and I walk my talk as you can see from my pictures.
If you’d like to learn for yourself, what I’ve learned about fat burning nutrition and getting your body fat level low enough so that you can finally see a “6 pack rack” of abs, then be sure to take a look at the Burn The Fat, Feed The Muscle program. Thousands of men and women call this their “fat loss bible.” For all the details, check out: www.BurnTheFat.com
Burn The Fat – Feed The Muscle is a downloadable e-book (340 pages) that will teach you how to burn fat, get leaner, and stay that way for life. It is one of the most thorough educational resources for this purpose.
Customer reviews of the Burn The Fat Program
Some Burn The Fat Customer reviews, testimonials and results achieved with the program, found on the web
- by Mark – Over a year ago I purchased Burn The Fat – Feed the Muscle. This program has had greater effect for me than any other program I’ve purchased. Fat loss is simple, but not easy and the guy offering this program is both honest and up-front about this fact and his product.
- by Bonnie – I am a 40 year old mom from South Africa. I have 3 children, aged 11, 6 and 4. My weight before was 85kg’s my body fat was 36.5%, size 40. I was fat and miserable, and my family life and my relationship were suffering. I was not able to do anything with my kids, and I was tired and constantly irritated.
I’ve always counted calories, but this just wasn’t working for me anymore. Someone my husband knows had done the Burn The Fat programme and it had changed his life, so I decided to do it too. I lost 15kg’s within 8 months and kept it off.
by Susie - Following the Burn The Fat guidelines I have lost over thirty pounds so far. I used to be a size 18 and now I’m a loose 12. I once weighed 202 pounds and now I’m only 165. Not only do I feel great on this program, but I also don’t feel deprived. My lifestyle has changed and I love the results I’m seeing at every level. Now I believe I can do more than what I previously thought I could so I’m re-evaluating my goals.
by Susie – In the one month using this product I’ve lost eight pounds, four inches from my waist and two percent of body fat. While I still have a ways to go I can’t believe how fast my stomach is shrinking. It is easy to see that I work out now. This program is the best.
Some more Burn The Fat Customer reviews, testimonials and results achieved with the program, found on the web
Tom Venuto’s Burn The Fat – Feed The Muscle book was the first ebook that I’ve ever purchased. I was skeptical after reading the website, but all of that was erased in an instant after reading the first chapter.
I spent 4 years in University studying the human body. I wish that BFFM was part of our curriculum because so many text books out there try to be politically correct and base their work on the Canada/American food guide.
For the past 5 years I have been calling BFFM my fat loss bible. I have referred to it countless times. Yes I have read and followed a few other diet programs in the past 18 months, but I find most of them just put some sort of twist on what Tom teaches.
Other books try to make dieting sound easy and effortless. I love Tom’s no BS approach. Tell me the truth. Tell me exactly what it’s going to take. Don’t sugar coat it. And give me the tools to help me stick to the program. That’s exactly what Burn The Fat – Feed The Muscle provides you with.
Tom’s genuine and sincere character shines in this book. He truly cares about us and wants us to succeed. No gimmicks, no quick fixes… it’s the down right honest truth.
Burn The Fat Feed The Muscle is a must read!
I can now fit into a pair of jeans which I haven’t fit in for years (38 European which is size 8 U.S. – I was a size 15 U.S.). The Salvation Army must love me these days, all the big clothes are placed in their recouperation dumpsters, bag upon bag of clothes. I’ve liberated 12 clothes hangers and two shelves full of oversized clothing since New Years!
Tom Venuto: 6 Nutrition Secrets For Great Abs is an article review from:Medicinezine.com
- MedicinEzine.com is a World Journal of medicine articles and reviews, product reviews, customer reviews and opinions. MedicinEzine.com provides the latest medical news and headlines from the world of medicine and healthcare today and tomorrow. MedicinEzine.com News
medser Sections for Tom Venuto – Burn That Fat Review
- Tom Venuto: Get Rid of that Stubborn Tummy Fat
- Tom Venuto’s Championship-Winning Ab Workout Routine
- Tom Venuto: 6 Nutrition Secrets For Great Abs
Tom Venuto is a lifetime natural bodybuilder, certified strength and conditioning specialist (CSCS) and a certified personal trainer (CPT). Tom is the author of “Burn the Fat, Feed The Muscle,” which teaches you how to get lean without drugs or supplements using methods of the world’s best bodybuilders and fitness models. Learn how to get rid of stubborn abdominal fat and increase your metabolism by visiting: www.BurnTheFat.com
Tom Venuto’s Championship-Winning Ab Workout Routine
In the first part of this series, we talked about the science behind revealing your abs and how it depends more on bodyfat levels than it does on abdominal training, per se. Now, let’s get into the real “meat” of getting great abs, training!
Personally, I only do about 15 minutes of ab work two times per week, with anywhere from two to four exercises for about 10-25 reps per exercise. Forget about thousands of reps of sit ups — it’s a waste of time. The reason my abs look the way they do is not from endless repetitions, but because I get my body fat down into the single digits with a highly specialized fat-burning diet program.
Here’s a recent ab routine that I’ve used (for bodybuilding/ ab-development purposes). I do this routine only twice a week and I change the exercises approximately every month so my body doesn’t adapt. I prefer slightly higher rep range than other muscle groups, but as you can see, it is far from doing a thousand reps a day.
A1. Hanging leg raises – 3 sets, 15-20 reps
Superset to:
A2. Hanging knee ups (bent-knee leg raises) -3 sets, 15-20 reps
(no rest between supersetted exercises A1 & A2, 60 sec. between supersets)
B1. Weighted swiss ball crunches (or weighted cable crunches) – 3 sets, 15-20 reps
Superset to:
B2. Incline bench reverse crunches – 3 sets, 15-20 reps
(no rest between supersetted exercises B1 & B2, 60 sec. between supersets)
How To Use Cardio For MAXIMUM Fat-Burning
Times have changed since the Aerobics revolution of the 1970′s and 1980′s. For years, aerobics was the darling of the fitness world. Then scientists began to acknowledge the benefits of weight training – for everyone, not just for bodybuilders.
Recently, the pendulum has swung the other direction and we’ve actually started hearing fitness “experts” suggesting that cardio should be kept to a minimum or even avoided completely. That’s the way things tend to go in the fitness world – they swing back and forth in trends, from one extreme to another. Lots of cardio or no cardio.
I suggest you avoid trend-hopping and pay close attention to what actually works, by people who know what they are talking about (such as bodybuilders, who are the leanest muscular athletes in the world). Doing nothing but cardio is a mistake. But cutting our cardio completely is also a mistake. The truth lies in the middle. Maximum fat burning occurs when you combine cardio training and weight training together.
Those who are genetically gifted with above average metabolisms will find that a slight drop in food intake and just a few days a week of cardio will usually do the trick. However, most people who are struggling with fat loss (sometimes referred to as “endomorph” body type) are simply NOT burning enough calories to get the results they want. The answer for them is more activity to burn more calories.
For health and weight maintenance, I would suggest 3 short cardio workouts per week, about 20-30 minutes per session. But for maximum fat loss, I recommend 4-7 days per week of cardio or other physical activity for 30-45 minutes (based on results), at a moderate pace. You can mix up the type of cardio you do, or choose the type you enjoy the most – stationary cycling, stairclimbing, elliptical machines, aerobic classes and other continuous activities are all excellent fat burners (it doesn’t have to be indoors or on a cardio machine).
If time efficiency is a concern for you, you could do 2-3 of those cardio workouts as high intensity interval training and you’ll achieve very good results even with briefer workouts. Even as little as 20-25 minutes per session can get great results IF your intensity level is high enough. Remember, seeing your abs is about low body fat. Low body fat is about burning calories and creating a calorie deficit. The calorie deficit is created by increasing the number of calories you burn and or decreasing the amount of calories you take in from food. Increasing intensity is one way to burn more calories in less time.
Let me reiterate what I said in the introduction. The reason my abs look the way they do is not solely from my training program, but because I get my body fat down into the single digits with a highly specialized fat-burning diet program.
Proper nutrition strategies are essential for revealing your abs, which is why the final installment of this series will be solely about nutrition.
If you would like to finally see your abs by burning body fat using Tom Venuto’s best-selling fat loss program, check out: www.BurnTheFat.com
Burn The Fat – Feed The Muscle is a downloadable e-book (340 pages) that will teach you how to burn fat, get leaner, and stay that way for life. It is one of the most thorough educational resources for this purpose.
Customer reviews of the Burn The Fat Program
Some Burn The Fat Customer reviews, testimonials and results achieved with the program, found on the web
- by Mark – Over a year ago I purchased Burn The Fat – Feed the Muscle. This program has had greater effect for me than any other program I’ve purchased. Fat loss is simple, but not easy and the guy offering this program is both honest and up-front about this fact and his product.
- by Bonnie – I am a 40 year old mom from South Africa. I have 3 children, aged 11, 6 and 4. My weight before was 85kg’s my body fat was 36.5%, size 40. I was fat and miserable, and my family life and my relationship were suffering. I was not able to do anything with my kids, and I was tired and constantly irritated.
I’ve always counted calories, but this just wasn’t working for me anymore. Someone my husband knows had done the Burn The Fat programme and it had changed his life, so I decided to do it too. I lost 15kg’s within 8 months and kept it off.
by Susie - Following the Burn The Fat guidelines I have lost over thirty pounds so far. I used to be a size 18 and now I’m a loose 12. I once weighed 202 pounds and now I’m only 165. Not only do I feel great on this program, but I also don’t feel deprived. My lifestyle has changed and I love the results I’m seeing at every level. Now I believe I can do more than what I previously thought I could so I’m re-evaluating my goals.
by Susie – In the one month using this product I’ve lost eight pounds, four inches from my waist and two percent of body fat. While I still have a ways to go I can’t believe how fast my stomach is shrinking. It is easy to see that I work out now. This program is the best.
Some more Burn The Fat Customer reviews, testimonials and results achieved with the program, found on the web
Tom Venuto’s Burn The Fat – Feed The Muscle book was the first ebook that I’ve ever purchased. I was skeptical after reading the website, but all of that was erased in an instant after reading the first chapter.
I spent 4 years in University studying the human body. I wish that BFFM was part of our curriculum because so many text books out there try to be politically correct and base their work on the Canada/American food guide.
For the past 5 years I have been calling BFFM my fat loss bible. I have referred to it countless times. Yes I have read and followed a few other diet programs in the past 18 months, but I find most of them just put some sort of twist on what Tom teaches.
Other books try to make dieting sound easy and effortless. I love Tom’s no BS approach. Tell me the truth. Tell me exactly what it’s going to take. Don’t sugar coat it. And give me the tools to help me stick to the program. That’s exactly what Burn The Fat – Feed The Muscle provides you with.
Tom’s genuine and sincere character shines in this book. He truly cares about us and wants us to succeed. No gimmicks, no quick fixes… it’s the down right honest truth.
Burn The Fat Feed The Muscle is a must read!
I can now fit into a pair of jeans which I haven’t fit in for years (38 European which is size 8 U.S. – I was a size 15 U.S.). The Salvation Army must love me these days, all the big clothes are placed in their recouperation dumpsters, bag upon bag of clothes. I’ve liberated 12 clothes hangers and two shelves full of oversized clothing since New Years!
Tom Venuto’s Championship-Winning Ab Workout Routine is an article review from:Medicinezine.com
- MedicinEzine.com is a World Journal of medicine articles and reviews, product reviews, customer reviews and opinions. MedicinEzine.com provides the latest medical news and headlines from the world of medicine and healthcare today and tomorrow. MedicinEzine.com News
medser Sections for Tom Venuto – Burn That Fat Review
- Tom Venuto: Get Rid of that Stubborn Tummy Fat
- Tom Venuto’s Championship-Winning Ab Workout Routine
- Tom Venuto: 6 Nutrition Secrets For Great Abs
Tom Venuto is a lifetime natural bodybuilder, certified strength and conditioning specialist (CSCS) and a certified personal trainer (CPT). Tom is the author of “Burn the Fat, Feed The Muscle,” which teaches you how to get lean without drugs or supplements using methods of the world’s best bodybuilders and fitness models. Learn how to get rid of stubborn abdominal fat and increase your metabolism by visiting: www.BurnTheFat.com
How to Get Rid of Your Abdominal Fat?
After 18 years in the fitness business, “How do I get great abs?”is still BY FAR the most frequently asked question I receive out of the 30,000+ emails that come into my office every month. No doubt, it’s because abs are the one body part that most people are the most frustrated with. Although their questions are often phrased differently and each person’s situation seems unique, my answer to “how do I get great abs” is almost always the same and you’re about to hear it…
“1,000 Sit-Ups And Crunches A Day and Still No Abs!”
One question I received recently REALLY got my attention because a young guy told me he was doing 1,000 crunches and sit ups a day and said he still couldn’t see his abdominals. He wrote:
“Tom: I have been working out for around a year now and I cannot get my lower abs into any type of shape. I’m starting to see my upper abs a little bit, which is great, but despite doing 900 various crunches, ab roller, and 100 sit-ups four days a week, along with my regular workout on the weights, I still have a tire around my waist. What else can I do?”
What did I tell him? Well, I gave him the same answer I’ve given thousands of people over the years, which is
…the only true “Secret” to great abs…
It takes training to increase strength, build endurance and DEVELOP the abdominals, but to SEE the definition in your abdominals – or any other muscle group for that matter – is almost entirely the result of low body fat levels.
This may sound counter-intuitive, but if you can’t see your abs, it’s not an issue of “muscle development” at all. You simply have too much body fat covering up the ab muscles. The lower abdominal area also happens to be the one place that most people – especially men – store the body fat first.
There’s a Scientific Reason Why Your Lower Ab Flab Is The Last Place To Go:
Most people don’t have their fat distributed evenly throughout their bodies. Each of us inherits a genetically determined and hormonally-influenced pattern of fat storage just as we inherit our eye or hair color. In other words, the fat seems to “stick” to certain areas more than others.
There’s a scientific reason for this. Your fat cells are not just inert “storage tanks” for excess fuel. They are actually endocrine glands which send and receive signals from the rest of the body. You could say that your fat cells “talk to your body” and your body “talks to your fat cells.” This occurs through a hormone and receptor system.
For body fat loss to occur, you must first get the fat cell (adipocyte) to release the fat into the bloodstream. THEN, the free fatty acids must be delivered to the working muscles where they are burned for energy.
For fat to be released, the hormone adrenaline (epinephrine) must be secreted and send a signal to your fat cells. Your fat cells receive this hormonal signal via adrenaline receptors called adrenoreceptors.
Fat cells have Beta 1 (B1) and Alpha 2 (A2) receptors. B1 receptors are the good guys. They activate hormone sensitive lipase, the enzyme that breaks down the fat and allows it to be released into the bloodstream to be burned. A2 receptors are the bad guys. They block the fat-releasing enzymes in the fat cell and encourage body fat formation.
How Body Fat Storage Patterns Affect You And Keep Your Abs From Showing
What’s the point of all the physiology? Well, it turns out that in men, the lower abdominal region has a higher concentration of A2 receptors, so this gives us one possible explanation of why the lower abdominal region is often the first place the fat goes when you gain it, and the last place it comes off when you’re losing it. (Incidentally, the fat in women’s hips and thighs is also higher in A2 receptors). This situation is dictated by genetics and by the hormonal and enzymatic pathways we discussed.
Think of tummy fat like the deep end of the swimming pool. No matter how much you protest, there is no way you can drain the deep end before the shallow end. However, don’t let this discourage you. Lower ab fat WILL come off, it will simply be the last place to come off. First place on – last place off.
This helps to explain why abdominal exercises have little impact on body fat loss. It’s a huge mistake to think that hundreds or thousands of reps of ab exercises will remove lower abdominal fat, except to the degree that it burns calories and contributes to the calorie deficit. What removes the fat – all over your body – is a calorie deficit and that comes from decreasing food intake, increasing activity, or a combination of both.
So What Should We Do?
What I suggested to this young man was cutting back the ab training, spending the time he was wasting on excess ab exercises for more intense, calorie-burning cardio and weight training for the rest of the body. I also suggested he do an accounting of his food intake, get his nutrition in order and decrease his calories slightly if necessary.
As it turned out, his diet was a mess, and as nutrition experts like to say, “You can’t out-train a lousy diet.”
It’s a monumental error to think that 1,000 reps of ab work a day will make your abs finally “pop” when your diet is a disaster and that’s leading to fat storage. It’s not that ab exercises aren’t important. But all the ab exercises in the world won’t help as long as you still have body fat covering the muscles. You can’t “spot reduce” with abdominal exercise and YOU CAN’T SEE YOUR ABS THROUGH A LAYER OF BODY FAT!
If you would like to finally see your abs by burning body fat using Tom Venuto’s best-selling fat loss program, check out: www.BurnTheFat.com
Burn The Fat – Feed The Muscle is a downloadable e-book (340 pages) that will teach you how to burn fat, get leaner, and stay that way for life. It is one of the most thorough educational resources for this purpose.
Customer reviews of the Burn The Fat Program
Some Burn The Fat Customer reviews, testimonials and results achieved with the program, found on the web
- by Mark – Over a year ago I purchased Burn The Fat – Feed the Muscle. This program has had greater effect for me than any other program I’ve purchased. Fat loss is simple, but not easy and the guy offering this program is both honest and up-front about this fact and his product.
- by Bonnie – I am a 40 year old mom from South Africa. I have 3 children, aged 11, 6 and 4. My weight before was 85kg’s my body fat was 36.5%, size 40. I was fat and miserable, and my family life and my relationship were suffering. I was not able to do anything with my kids, and I was tired and constantly irritated.
I’ve always counted calories, but this just wasn’t working for me anymore. Someone my husband knows had done the Burn The Fat programme and it had changed his life, so I decided to do it too. I lost 15kg’s within 8 months and kept it off.
by Susie - Following the Burn The Fat guidelines I have lost over thirty pounds so far. I used to be a size 18 and now I’m a loose 12. I once weighed 202 pounds and now I’m only 165. Not only do I feel great on this program, but I also don’t feel deprived. My lifestyle has changed and I love the results I’m seeing at every level. Now I believe I can do more than what I previously thought I could so I’m re-evaluating my goals.
by Susie – In the one month using this product I’ve lost eight pounds, four inches from my waist and two percent of body fat. While I still have a ways to go I can’t believe how fast my stomach is shrinking. It is easy to see that I work out now. This program is the best.
Some more Burn The Fat Customer reviews, testimonials and results achieved with the program, found on the web
Tom Venuto’s Burn The Fat – Feed The Muscle book was the first ebook that I’ve ever purchased. I was skeptical after reading the website, but all of that was erased in an instant after reading the first chapter.
I spent 4 years in University studying the human body. I wish that BFFM was part of our curriculum because so many text books out there try to be politically correct and base their work on the Canada/American food guide.
For the past 5 years I have been calling BFFM my fat loss bible. I have referred to it countless times. Yes I have read and followed a few other diet programs in the past 18 months, but I find most of them just put some sort of twist on what Tom teaches.
Other books try to make dieting sound easy and effortless. I love Tom’s no BS approach. Tell me the truth. Tell me exactly what it’s going to take. Don’t sugar coat it. And give me the tools to help me stick to the program. That’s exactly what BFFM provides you with.
Tom’s genuine and sincere character shines in this book. He truly cares about us and wants us to succeed. No gimmicks, no quick fixes… it’s the down right honest truth.
Burn The Fat Feed The Muscle is a must read!
I can now fit into a pair of jeans which I haven’t fit in for years (38 European which is size 8 U.S. – I was a size 15 U.S.). The Salvation Army must love me these days, all the big clothes are placed in their recouperation dumpsters, bag upon bag of clothes. I’ve liberated 12 clothes hangers and two shelves full of oversized clothing since New Years!
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Tom Venuto: Get Rid of that Stubborn Tummy Fat is an article review from:Medicinezine.com
- MedicinEzine.com is a World Journal of medicine articles and reviews, product reviews, customer reviews and opinions. MedicinEzine.com provides the latest medical news and headlines from the world of medicine and healthcare today and tomorrow. MedicinEzine.com News
